Job Function
- Research & Development
Discipline
- Medical Sciences
- Medicine
- Pharmacy
Years of Experience
- 4-6 years
Job Details
Responsibilities
- Working closely with Medicinal Chemistry/Biologics Discovery/in vitro Pharmacology teams developing in vivo models to test the activity of test articles and perform in-depth characterization of mechanism studies in these models;
- Collaborate with the broader scientific teams to design and execution vivoPoC experiments aiming at defining the mechanism(s) of action of test articles;
- Perform in-depth literature search, design/execute immunology in vivo models exploring the PD of test articles supporting differentiation points identification/ indication expansion;
- Serve as representative of immunology in vivo team in the project team responsible for addressing technique issues/giving suggestions to support achieving key milestones;
- Responsible for experiment tissue collection/biomarker assessment/data analysis/experiment report drafting/IND submission material drafting;
- Support new target evaluation, MoA analysis and proposal preparation.
Requirements
- Master or PhD degree in the field of immunology, immuno-oncology, pharmacology or veterinary medicine with at least three years (for PhD level candidates) or six years (for Master level candidates) of working experience in industry settings (TopCROs/Pharma/Bio-Pharma/Biotech).
- Strong publication/patent track records are preferred.
- Experience in independently leading immunology & inflammation in vivo projects to PCC/IND milestones are highly preferred.
- Hands-on experience and in-depth knowledge in vivo animal models of inflammatory/autoimmune diseases or Immuno-oncology, proficient in routine animal experiment/handlings kills.
- Hands-on experience and in-depth knowledge in exvivoimmunology/molecular assays/techniques including flow cytometry, ELISA,MSD, Luminex, CBA, western blot, IHC/IF, qPCRetc.
- Experience in sequencing(DNA/RNA)or proteomics data analysis or mathematic/computational modeling is a plus.
- Strong ability in literature/patent search, analytical thinking and problem solving.
- Good verbal/reading/writing skills in English as proved by CET6/IELTS/TOEFL/GRE scores.
- Excellent analytical, organizational and communications skills with demonstrated ability to work collaboratively with peers across multiple functions.
About the Company
Overview
Simcere Pharmaceutical Group Limited (2096.HK) is a pharmaceutical company driven by innovative R&D. We are committed to "For patients, for life." across the following core therapeutic areas: oncology, central nervous system, autoimmunity and anti-infection. Furthermore, we are also actively expanding our presence in disease areas with significant clinical needs in the future.
Our industry-leading capabilities and commitment to synergistic innovation have also enabled various strategic collaborations and we are seen as the partner of choice by innovative biopharmaceutical companies, medical institutes, and research teams in China and globally.